p53

best video: p53
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Mutations in P53 tumor suppressor are the commonest in human cancer. The protein controls various cellular processes such as DNA repair and apoptosis, and functions as the guardian
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The most popular links about p53 (by google opininon):

UF researchers identify key target for cancer therapies - Media Newswire press release

Their study revealed that mutations in the tumor-suppressing p53 protein lead to overabundance of a second protein called focal adhesion kinase, or FAK, ...
http://media-newswire.com/release_1064179.html

A clinicopathological study of 45 cases with p53 immunohistochemistry

BACKGROUND : Brainstem tumors represent 10% of central nervous system tumors, accounting for 30% of pediatric posterior fossa tumors. AIMS : The aim of this study was to clinicopathologically correlate 45 cases of brain stem gliomas and determine t
http://glioma-cancer.com/2008/04/18/a-clinicopathological-study-of-45-cases-with-p53-immunohistochemistry/

Landbank lends P320M to LGU projs in Negros Philippine Star via Yahoo! Philippines News

The Land Bank of the Philippines is extending a total of P320-million in loans to finance various local government development projects in Negros Occidental.
http://beta.ph.news.yahoo.com/star/20080425/tbs-landbank-lgu-negros-0ec9746.html

25 Hottest Schools - 'How To Get Into College Guide'

LAWFUEL - Latest from Newsweek - "25 Hottest Schools" p. 53. In this excerpt from the annual Newsweek/ Kaplan "How to Get Into College Guide," Contributing Editor Jay Mathews lists the "25 Hottest Schools." The list highlig
http://www.lawfuel.com/show-release.asp?ID=14172

p53 protein - Wikipedia, the free encyclopedia

p53, also known as protein 53 TP53, is a transcription factor that regulates the cell cycle and hence functions as a tumor suppressor. ...
http://en.wikipedia.org/wiki/P53

p53

p53 AND HUMAN CANCERS. p53 is a nuclear phosphoprotein which acts as a tumor suppressor. The gene for p53 is located on the short arm of chromosome 17 at 17p13.105-p12.
http://www.bioscience.org/news/scientis/p53.htm

InterPro: IPR012346 p53 and RUNT-type transcription factor, ...

InterPro: IPR012346 p53 and RUNT-type transcription factor, DNA-binding ... Parent IPR008967 p53-like transcription factor, DNA-binding ...
http://www.ebi.ac.uk/interpro/IEntry?ac=IPR012346

New Phase III Data Confirm Phase II Findings of ADVEXIN ? Efficacy - Business Wire press release

Biomarkers of the p53 tumor suppressor gene target of ADVEXIN treatment were predictive in selecting patients more likely to respond to ADVEXIN, ...
http://www.businesswire.com/news/google/20080413005049/en

2 stem cell patents issued last week

View this message online Dear manoj kumar valluru, Last week 2 patents of relevance to the area of stem cells were issued. 7,357,929 Patent Spotlight, teaches antibodies to placental growth factor are useful agains osteoporosis. 7,358,08
http://stemcellbiology.blogspot.com/2008/04/2-stem-cell-patents-issued-last-week_20.html

Teves may yet again be bypassed by CA due to P53.7-B revenue shortfall GMA News

MANILA, Philippines - The continued shortfall in government"s revenue collections may yet again be the cause of another delay in the confirmation of Finance Secretary Margarito Teves" appointment, a congressman-member of the Commission on Appointments sai
http://www.gmanews.tv/story/90429/Teves-may-yet-again-be-bypassed-by-CA-due-to-P537-B-revenue-shortfall

Gene Thought to Assist Chemo May Help Cancer Thrive

A gene thought to be essential in helping chemotherapy kill cancer cells, may actually help them thrive. In a new study of chemo patients, scientists at Georgia Tech and the Ovarian Cancer Institute found that 70 percent of subjects whose tumors had mutat
http://www.gatech.edu/news-room/release.php?id=1379

Loss of p53 Induces Changes in the Behavior of Subventricular Zone ...

Jan 25, 2006 ... This study addresses these questions in mice carrying the deletion of p53, a tumor-suppressor gene expressed in the SVZ. We show here that, ...
http://www.jneurosci.org/cgi/content/full/26/4/1107

The Cell Cycle

p53. The p53 protein senses DNA damage and can halt progression of the cell cycle in G 1 by blocking the activity of CDK2 . Both copies of the p53 gene must be mutated for this to fail ...
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/CellCycle.html

TP53 - Tumor protein p53 Li-Fraumeni syndrome - aka: p53, P53 - ...

Tumor protein p53 Li-Fraumeni syndrome ... Identification and classification of p53-regulated genes Proc Natl Acad Sci USA. 1999
http://www.cancerindex.org/geneweb/TP53.htm

Fungicide developed to control disease of chrysanthemums - GMA news.tv

Besides being as effective as commercial fungicides, the hyperparasites are also cheaper, allowing flower growers to earn as much as P53,000 per hectare of ...
http://www.gmanews.tv/story/91835/Fungicide-developed-to-control-disease-of-chrysanthemums

From a Nurse: How to Treat Pimples on the Cheap and Keep It Natural

From a Nurse: How to Treat Pimples on the Cheap and Keep It Natural April 18th, 2008 by filia6730 diet vegetarian high protein.It??s easy to treat acne cheaply, simply, naturally yet effective, at home. This simple, cheap and yet the best, alternative
http://filia6730.fandomspot.com/2008/04/18/from-a-nurse-how-to-treat-pimples-on-the-cheap-and-keep-it-natural/

Development in South Sound ? April 27 The Olympian

OLYMPIA
http://www.theolympian.com/business/story/430434.html

Molecules That Control Our Cancer Destiny

The p53 gene wields the power of life and death over cells in our body.
http://empty-nest.contentquake.com/2007/03/08/molecules-that-control-our-cancer-destiny/

IARC TP53 DATABASE - Welcome

Petitjean A, Mathe E, Kato S, Ishioka C, Tavtigian SV, Hainaut P, Olivier M. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor ...
http://www-p53.iarc.fr/

P53 Analysis by BRT Laboratories

BRT Laboratories provides clinical testing services including p53 Analysis ?? a key component of the body??s anti-tumor defense.
http://www.brtlabs.com/P53.html

p53_web_site

Everything you want to know on p53: p53 mutations database: p53 information...
http://p53.free.fr/

MDM2 gene SNP309 T/G and p53 gene SNP72 G/C do not influence ... - 7thSpace Interactive press release

SNP309 T/G rs2279744 causes higher levels of MDM2, the most important negative regulator of the p53 tumor suppressor. SNP72 G/C rs1042522 gives rise to ...
http://7thspace.com/headlines/279610/mdm2_gene_snp309_tg_and_p53_gene_snp72_gc_do_not_influence_diffuse_large_b_cell_non_hodgkin_lymphoma_onset_or_survival_in_central_european_caucasians.html

beware of the PANTHERdb!

Once in a while i like going around the web looking for cool tools that can be used in research, but also just to visualize scientific knowledge. With the amount of our knowledge, and the size of our databases increasing daily, I find it quite useful to b
http://skeptalchemist.blogspot.com/2008/04/beware-of-pantherdb.html

Fungicide developed to control disease of chrysanthemums GMA News

LA TRINIDAD, Benguet - Researchers from the Benguet State University BSU have developed "fungal hyperparasites" to control white rust, considered as the most destructive disease of chrysanthemums.
http://www.gmanews.tv/story/91835/Fungicide-developed-to-control-disease-of-chrysanthemums

Study details regulation of vital tumor suppressor gene p53

So vital is the p53 tumor suppressor gene in controlling cancer that its dysfunction is linked to more than half of human cancers. At the same time, the gene??s capacity for shutting down cell growth, even causing cells to commit suicide if necessary, is
http://breakthroughdigest.com/study-details-regulation-of-vital-tumor-suppressor-gene-p53/

Definition: p53 from Online Medical Dictionary

Previous: p34PSK-J3 kinase, p35, p36, P400 protein, p42mapk kinase, p49 3F12 kinase Next: p53-activating kinase, p54 protein kinase, p57lck ...
http://128.240.24.212/cgi-bin/omd?p53

The p53 tumor suppressor protein

Genes and Disease provides an introduction to the relationship between genetic factors and human disease with a summary of 60 genetic diseases with links to related ...
http://www.ncbi.nlm.nih.gov/disease/p53.html

IARC TP53 DATABASE - Welcome

Functional and structural properties of p53 mutant proteins ... The p53 Gateway, a new web site dedicated to p53 translational research, was ...
http://www-p53.iarc.fr/

New pre-clinical data out at conference - Seattle Post Intelligencer

... of their levels of a protein known as p53. Patients who have low levels of p53 are less responsive to standard therapy. Read the company&39s release here.
http://blog.seattlepi.nwsource.com/thelifesciencesblog/archives/136539.asp

Effect of p53 codon 72 genotype on breast cancer survival depends on p53 gene status.

Effect of p53 codon 72 genotype on breast cancer survival depends on p53 gene status. April 20th, 2008 by admin in gene status, gene, survival, genotype, Effect, p53 codon 72, breast cancer ? Breast Center, Beijing Cancer Hospital and Institute, Pek
http://www.cancer2blog.com/effect-of-p53-codon-72-genotype-on-breast-cancer-survival-depends-on-p53-gene-status/

Is DDB Selecta??s new flavor of the month? Philippine Daily Inquirer

DDB has reportedly been verbally advised by clients that it won an ???all-or-nothing??? Unilever Selecta Ice Cream pitch against two big agencies: incumbent McCann-Erickson and Lowe Worldwide.
http://business.inquirer.net/money/features/view/20080425-132575/Is-DDB-Selectas-new-flavor-of-the-month

Cell's Fight Against Cancer Revealed

If anything in cancer biology can be likened to a cage match, this is it: the battle inside the cell walls between LTag, "The Most Amazing Molecule in the Universe," and p53, "The Guardian of the Genome."
http://www.physorg.com/news76265016.html

Database of germline p53 mutations

Database of germline p53 mutations. ... Database of germline p53 mutations - table file is in Microsoft Excel format 635 kB
http://www.lf2.cuni.cz/projects/germline_mut_p53.htm

p53 Gateway

The p53 Gateway is a regularly updated resource designed to facilitate p53 translational research and clinical applications.
http://p53gateway.org/

p53 protein - Wikipedia, the free encyclopedia

In 1993, p53 was voted molecule of the year by Science magazine. ... Retrieved from " http://en.wikipedia.org/wiki/P53_%28pro ...
http://en.wikipedia.org/wiki/P53

One Hormone Used In Hormone Replacement Therapy Linked To Breast ... - Science Daily press release

Hyder&39s team found similar results using PRIMA, which re-activated a protein known as p53. When p53 was activated within tumor cells, the number of breast ...
http://www.sciencedaily.com/releases/2008/04/080401161625.htm

Case for Three Detectives

Bruce, Leo. Case For Three Detectives. Chicago: Academy Chicago, 1936. First things first: Leo Bruce is actually a pseudonym for Rupert Croft-Cooke. Just had to get that out there. Second, I have to say how disappointed I am to not be up on my myster
http://gr4c5.wordpress.com/2008/04/20/case-for-three-detectives/

Negros Occidental gets P320M in Land Bank loans Philippine Daily Inquirer

Government-owned Land Bank of the Philippines said it had approved P320 million in loans for infrastructure and development projects in the central Philippines province of Negros Occidental.
http://business.inquirer.net/money/breakingnews/view/20080429-133338/Negros-Occidental-gets-P320M-in-Land-Bank-loans

Coffee Drinkers Rejoice! Caffeine & Exercise Can Help Prevent Skin Cancer

A study at Rutgers University studied the effects of caffeine combined with exercise. What they found was very surprising. When used together, exercise and caffeine doubled the levels of a tumor-suppressing proteinphospho-p53.
http://fitnessblackbook.com/aerobic-exercise/coffee-drinkers-rejoice-caffeine-exercise-reduce-skin-cancer-risks/

p53 - tumor suppressor protein

THE p53 GENE like the Rb gene, is a tumor suppressor gene, i.e., its activity stops the formation of tumors. If a person inherits only one functional copy ...
http://www.ncbi.nlm.nih.gov/disease/p53.html

p53

DNA Sequence. Protein Sequence. Isoforms. Mutations. Polymorphisms. Haplotypes. p53-Related Molecules ... p53 &gt Polymorphisms. Maintained By: p53 KnowledgeBase ...
http://p53.bii.a-star.edu.sg/aboutp53/snps/snpdetail.php?geneid=X54156&snppos=14766

p53 - A Tumor-Suppressor Protein

Mutations in the p53 tumor suppressor protein are the most commonly observed genetic alterations in human cancer.
http://cti.itc.virginia.edu/cmg/Demo/pdb/p53/p53.html

Preclinical Study Shows CTI&39s Brostallicin&39s Cancer-Killing ... - PR Newswire press release

P53 is a protein that regulates the cell cycle and acts as a tumor suppressor. Patient tumors that have low or absent p53 are less responsive to standard ...
http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/04-15-2008/0004792596&EDATE=

Researchers identify key target for cancer therapies 4/21/2008

New therapies must target a key protein interaction to destroy aggressive cancer cells?? protective force field, University of Florida scientists reported this week at the American Association for Cancer Research??s annual meeting in San Diego. The ba
http://blog.find-group.com/?p=1292

Stuart Petroleum Releases March 2008 Quarter Activities Report STU.AX, 00836412, 20080429 Huntleys' Stock of the Week via Yahoo!7 Finance

Stuart Petroleum provided March 2008 quarterly activities report, reporting quarterly sales revenue of 17.3m, the second highest on record. Stuart's share of production during the quarter was 175,760bbl. At Gippsland Basin Permit VIC P53, the company com
http://au.biz.yahoo.com/080429/38/1pxv3.html

Cancer may have met its match in the p53 gene

"This does not mean that such a therapy would be inefficient, but it would be unlikely to be as effective as the methods used by these investigators" in the lab tests on mice, writes Serrano in The New England Journal of Medicine.
http://www.webmd.com/cancer/news/20070509/turn-on-gene-turn-off-cancer

The p53 Web Site

Everything you want to know on p53: p53 mutations database: p53 information.
http://p53.free.fr/

InterPro: IPR002117 p53 tumor antigen

The European ... p53 has been implicated in cell cycle regulation, particularly in ... p53 is a sequence-specific DNA-binding protein and ...
http://www.ebi.ac.uk/interpro/IEntry?ac=IPR002117

The Challenge of p53: Linking Biochemistry, Biology, and Patient ...

The Challenge of p53: Linking Biochemistry, Biology, and Patient Management ... p53 &8226 Stress responses &8226 Physiology &8226 Biochemistry &8226 ...
http://stemcells.alphamedpress.org/cgi/content/abstract/16/4/248

Early onset lung cancer, cigarette smoking and the SNP309 of the ... - 7thSpace Interactive press release

The MDM2 protein is a key inhibitor of p53 and several mechanisms of MDM2/p53 interactions are presently known: modulating DNA-repair, cell-cycle control, ...
http://7thspace.com/headlines/279603/early_onset_lung_cancer_cigarette_smoking_and_the_snp309_of_the_murine_double_minute_2_mdm2_gene.html

Classroom management techniques for students with ADHD / Roger ??

David HReally interesting read I found today: Series: A step-by-step guide for educators LC4713.2 .P53 2008 at EDUCATION LIBRARY. Continue Reading
http://adhdreport.com/?p=19527

Negros Occidental LGUs get P320M loan for infra projects GMA News

MANILA, Philippines- Local government units in the province of Negros Occidental have been granted a P320-million loan for their infrastructure projects by state-owned lender Land Bank of the Philippines.
http://www.gmanews.tv/story/91333/Negros-Occidental-LGUs-get-P320M-loan-for-infra-projects

One Gene to Rule Them All

The p53 tumor suppressor gene prevents tumor growth, even when activated only briefly.
http://scienceblogs.com/grrlscientist/2007/01/post_7.php

p53 description

The p53 database contains information on nearly 5867 mutations found in the human p53 gene. The database itself has been updated in April of 1997. ...
http://www.ibiblio.org/dnam/des_p53.htm

P53 2008 Conference : Home

The 14th International p53 Workshop from October 27-31, 2008, will be held at Fudan Crowne Plaza, Fudan University, Shanghai City, China.
http://156.145.233.133/p53

P53 protein - Wikipedia, the free encyclopedia

... p53, also known as protein 53 TP53, is a transcription factor that regulates the cell cycle and hence functions as a tumor suppressor. It is ...
http://en.wikipedia.org/wiki/P53_protein

Cell Therapeutics` Brostallicin Kills Colon, Ovarian Cancer Cells ... - RTT News

The company noted that the study suggested that brostallicin is more effective in cells with normal p53 status and added that cells with abnormal or missing ...
http://www.rttnews.com/sp/breakingnews.asp?date=04/15/2008&item=44&vid=0

breast cancer research operable carcinoma bcl 2 breast cancer clinical response

Clinical response after two cycles compared to HER2, Ki-67, p53, and bcl-2 in independently predicting a pathological complete response after preoperative chemotherapy in patients with operable carcinoma of the breast Filed under: Breast Cancer Research ?
http://www.minisky.net/2008/04/28/breast-cancer-research-operable-carcinoma-bcl-2-breast-cancer-clinical-response/

Baguio smoke-belching rampant Manila Bulletin

BAGUIO CITY ?? Two-thirds of the motor vehicles plying various streets in this mountain resort city are emitting smoke which does not pass the standards set by the Clean Air Act, and as a result, the air quality in this city worsens every day.
http://www.mb.com.ph/SP_PROV20080428.html

Cancer Breakthrough - Scientists restore gene to shrink tumors in mice

Reactivating a gene that normally suppresses the growth of tumors may be an effective way to treat cancers, scientists said on Wednesday. The gene called p53 is a leading tumor suppressor which stops damaged cells from dividing. In the majority of human c
http://today.reuters.com/news/articlenews.aspx?type=topNews&storyID=2007-01-24T205650Z_01_L24297150_RTRUKOC_0_US-CANCER-GENE.xml

genome.gov Talking Glossary: "p53"

<< Back to the glossary. Pronounciation of p53 ... Dr. Francis Collins, director of the National Human Genome Research Institute, defines p53. related ...
http://www.genome.gov/glossary.cfm?key=p53

RCSB Protein Data Bank

p53 tumor suppressor is one of our defenses against this type of damage. ... but when DNA damage is sensed, p53 levels rise and initiate protective measures. ...
http://www.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb31_1.html

Pfam: Family: P53_TAD PF08563

The binding of the p53 transactivation domain by regulatory proteins regulates p53 transcription activation. This motif is comprised of a ...
http://pfam.sanger.ac.uk/family?acc=PF08563